TITLE:
Comparative Efficacy of Tagetes erecta and Centella asiatica Extracts on Wound Healing in Albino Rats
AUTHORS:
Sandipan Chatterjee, Tigari Prakash, Dupadahalli Kotrsha, Nadendla Rama Rao, Divakar Goli
KEYWORDS:
Centella asiatica, Tagetes erecta, Excision, Incision, Dead Space Wound Model
JOURNAL NAME:
Chinese Medicine,
Vol.2 No.4,
December
9,
2011
ABSTRACT: The study was undertaken to evaluate the comparative efficacy of hydroalcoholic extracts of leaves of Tagetes erecta (T. erecta) and aerial parts of Centella asiatica (C. asiatica) on Excision, Incision and Dead space wound models in albino rats. Extract of T. erecta and C. asiatica (P T. erecta extract (250 and 500 mg/kg) showed significantly increased the wound breaking strength in incision wound model and wet and dry granulation tissue weights, breaking strength in a dead space wound model compare to control and C. asiatica treated group (P T. erecta extract showed potent wound healing activity then the reported C. asiatica in different wound parameters.