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Reich, D., Patterson, N., Campbell, D., Tandon, A., Mazieres, S., Ray, N., Parra, M.V., Rojas, W., Duque, C., Mesa, N. and García, L.F. (2012) Reconstructing Native American Population History. Nature, 488, 370-374.

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• TITLE: Type 2 Diabetes Phenotype in a Small Isolated Zapotec-Speaking Community in the Valley of Oaxaca, Southern Mexico

  AUTHORS: Bertis B. Little, Robert M. Malina, Maria Eugenia Peña Reyes, Christopher R. Tillquist, Elizabeth O’Brien, Richard A. Kerber

  KEYWORDS: T2DM Phenotype, Central Obesity, Sarcopenia, Grip Strength, Body Proportions

  JOURNAL NAME: Open Journal of Endocrine and Metabolic Diseases, Vol.10 No.9, September 29, 2020

  ABSTRACT: Objective: To test the hypothesis that the type 2 diabetes mellitus (T2DM) phenotype in an indigenous population is characterized by proportionally short legs and obesity. Methods: Anthropometric characteristics were compared in females and males with T2DM (n = 20, n = 8, respectively) and without T2DM (n = 117, n = 93, respectively). Factor analysis derived dimensions were regressed on T2DM in logistic regression. Results: Weight, sitting height ratio and hip circumference were significantly lower (p Conclusion: Reduced muscle strength/mass and increased central adiposity characterize the T2DM phenotype.