TITLE:
Type 2 Diabetes Phenotype in a Small Isolated Zapotec-Speaking Community in the Valley of Oaxaca, Southern Mexico
AUTHORS:
Bertis B. Little, Robert M. Malina, Maria Eugenia Peña Reyes, Christopher R. Tillquist, Elizabeth O’Brien, Richard A. Kerber
KEYWORDS:
T2DM Phenotype, Central Obesity, Sarcopenia, Grip Strength, Body Proportions
JOURNAL NAME:
Open Journal of Endocrine and Metabolic Diseases,
Vol.10 No.9,
September
29,
2020
ABSTRACT: Objective: To test the hypothesis that the type 2 diabetes mellitus (T2DM) phenotype in an indigenous population is characterized by proportionally short legs and obesity. Methods: Anthropometric characteristics were compared in females and males with T2DM (n = 20, n = 8, respectively) and without T2DM (n = 117, n = 93, respectively). Factor analysis derived dimensions were regressed on T2DM in logistic regression. Results: Weight, sitting height ratio and hip circumference were significantly lower (p Conclusion: Reduced muscle strength/mass and increased central adiposity characterize the T2DM phenotype.