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Luo, M., Liu, M., Mozdziesz, D., Lin, T., Dutschman, G., Gullen, E., Cheng, Y. and Sartorelli, A. (2000) Synthesis and Biological Evaluation of L- and D-Configuration 1,3-Dioxolane 5-azacytosine and 6-Azathymine Nucleosides. Bioorganic & Medicinal Chemistry Letters, 10, 2145-2148.
https://doi.org/10.1016/S0960-894X(00)00418-2
has been cited by the following article:
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TITLE:
Synthesis, Characterization, and Antioxidation Evaluation of Novel Spiro-5-(fluoren-9’-yl)-6-azauracil and Their N,N-Dialkyl Derivatives
AUTHORS:
Hafsa Sayed, Dina A. Bakhotmah
KEYWORDS:
N, N-Disubstituted, 6-Azauracil, Fluoren-9-One, 1, 2, 4-Triazine, Antioxidant
JOURNAL NAME:
International Journal of Organic Chemistry,
Vol.10 No.4,
November
27,
2020
ABSTRACT: In search for new antioxidant agents derived from 6-azauracil, the spiro-5-(flurin-9’-yl)-6-azauracil 3 and their N,N-disubstituted-6-azauracils 4 - 17 have been synthesized using various methods and reaction conditions. Structure of the new synthesized compounds was deduced from elemental analysis and spectral measurements, for example IR, 1H/13C NMR and mass spectroscopy. The antioxidant evaluation of the new targets showed that the activity increases in the order of 8 > 10 > 6 > 7 > 9 in comparison with 2,2-Diphenyl-1-picrylhydrazyl (DPPH) and ascorbic acid as standards.