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L. E. van Vlerken, Z. Duan, S. R. Little, M. V. Seiden and M. M. Amiji, “Biodistribution and Pharmacokinetic Analysis of Paclitaxel and Ceramide Administered in Multifunctional Polymer-Blend Nanoparticles in Drug Resistant Breast Cancer Model,” Molecular Pharmaceutics, Vol. 5, No. 4, 2008, pp. 516-526. doi:10.1021/mp800030k

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• TITLE: Recent Advances in Drug Delivery Systems

  AUTHORS: Nuno Martinho, Christiane Damgé, Catarina Pinto Reis

  KEYWORDS: Nanomedicine, Nanoparticles, Liposomes, Cyclodextrins, Dendrimers, ADEPT

  JOURNAL NAME: Journal of Biomaterials and Nanobiotechnology, Vol.2 No.5, December 9, 2011

  ABSTRACT: Drug targeting to specific organs and tissues has become one of the critical endeavors of the century since the use of free drugs in conventional dosage forms generally involves difficulties in achieving the target site at the appropriate dose after or during a proper time period. Consequently, the search for new drug delivery approaches and new modes of action represent one of the frontier research areas. New drug delivery systems include lipidic, proteic and polymeric technologies to provide new sustained drug delivery with better body distribution, drug protection from harsh external environment and avoidance of drug clearance. Many of these technologies have reached the market therefore proving the benefits of these new carriers. This review covers the generalities of those new carriers and their new advances in drug delivery.