TITLE:
Comparison of Cell Morphology and Flow Cytometry in the Diagnosis of Multiple Myeloma
AUTHORS:
Jun Lu, Chao Li, Yong Huang, Jiakui Zhang
KEYWORDS:
Multiple Myeloma, Cell Morphology, Flow Cytometry, Immune Classification
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.11 No.11,
November
24,
2020
ABSTRACT: Objective: To investigate the value of cell morphology and flow
cytometry in the diagnosis of Multiple myeloma (MM). Methods: 166 newly
diagnosed MM patients were retrospectively analyzed, and the proportion of
plasma cells detected by flow cytometry and cell morphology in these patients
was statistically analyzed. Results: All patients were divided into
three groups according to the proportion of plasma cells detected by cell
morphology: group A (≥30%), group B (≥10% and - CD38 + CDl38 + CD56 +/- CD45dim ~ -. Conclusion: There is a certain correlation between the two
detection methods. The quantitative detection of myeloma cells by cell
morphology is better, and the qualitative detection by flow cytometry is
better. Combined with the two detection methods, the detection rate of multiple
myeloma can be significantly improved.