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Stalmans, P., Benz, M.S., Gandorfer, A., Kampik, A., Girach, A., Pakola, S., et al. (2012) Enzymatic Vitreolysis with Ocriplasmin for Vitreomacular Traction and Macular Holes. New England Journal of Medicine, 367, 606-615.
https://doi.org/10.1056/NEJMoa1110823

has been cited by the following article:

• TITLE: Epidemiological Review of Macular Hole in Ekiti, Southwestern Nigeria

  AUTHORS: Iyiade A. Ajayi, Olusola J. Omotoye, Stella Adegbehingbe

  KEYWORDS: Macular Hole, Southwestern Nigeria, Epidemiological Review, Central Visual Defect

  JOURNAL NAME: Open Journal of Ophthalmology, Vol.10 No.4, November 10, 2020

  ABSTRACT: Background: Macular hole is a known cause of central visual defect with varying etiologies in different parts of the world. It was considered an untreatable condition until 1991 when varying treatment techniques began to emerge with resultant restoration of central vision. This study was carried out to evaluate the prevalence and pattern of Macular hole in a tertiary eye centre in Nigeria. Method: This is a prospective hospital-based study over a 5 year period spanning from November 2013 to October 2018. All patients with macular hole seen within this period were included in the study. Relevant data were recorded with a structured questionnaire and analysed with SPSS version 20. Results: There were 46 eyes of 42 patients which constituted about 0.5% of all new patients seen over the study period. Male to female ratio was 1:1.3 with age ranged between 15 and 91years (mean = 61.8 ± 16.5 years). The majority of the patients (95.7%) had Idiopathic macular hole. Half of the patients (54.8%) had visual acuity less than 3/60 in the affected eye at the time of presentation. The majority (95.7%) of the patients did not accept the recommended surgical treatment option because of financial incapacitation. Conclusion: Macular hole is a disease of marked visual consequence. Available treatment option is still not within the reach of the majority because of the high cost.