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Lewis, D.A., Travers, J.B., Somani, A.-K. and Spandau, D.F. (2010) The IGF-1/IGF-1R Signaling Axis in the Skin: A New Role for the Dermis in Aging-Associated Skin Cancer. Oncogene, 29, 1475-1485. https://doi.org/10.1038/onc.2009.440

has been cited by the following article:

• TITLE: Application of Synthetic Peptides to Improve Parameters of Skin Physiology: An Open Observational 30-Day Study

  AUTHORS: Neil Fisher, Davide Carati

  KEYWORDS: Peptides, Elasticity, Moisture, Skin, Topical

  JOURNAL NAME: Journal of Cosmetics, Dermatological Sciences and Applications, Vol.10 No.4, October 26, 2020

  ABSTRACT: We describe a novel, non-invasive peptide-based product intended to counter several pathophysiological signs of aged skin through the topical application of signalling molecule mimics. Several aesthetic parameters of skin physiology were assessed. The product was tested on 20 healthy Caucasian women (35 - 55 years-old) who applied the product twice-daily to the face for 30 days. Skin elasticity, firmness, sagging, brightness, and luminosity were assessed. Additionally, over a period of 3 hours, the hydrating effect of the product vs placebo vs non-treated skin was assessed. After 30 days, participants showed significant increases in skin elasticity (11.8% increase, p