TITLE:
Application of Synthetic Peptides to Improve Parameters of Skin Physiology: An Open Observational 30-Day Study
AUTHORS:
Neil Fisher, Davide Carati
KEYWORDS:
Peptides, Elasticity, Moisture, Skin, Topical
JOURNAL NAME:
Journal of Cosmetics, Dermatological Sciences and Applications,
Vol.10 No.4,
October
26,
2020
ABSTRACT: We describe a novel, non-invasive peptide-based product intended to counter several pathophysiological signs of aged skin through the topical application of signalling molecule mimics. Several aesthetic parameters of skin physiology were assessed. The product was tested on 20 healthy Caucasian women (35 - 55 years-old) who applied the product twice-daily to the face for 30 days. Skin elasticity, firmness, sagging, brightness, and luminosity were assessed. Additionally, over a period of 3 hours, the hydrating effect of the product vs placebo vs non-treated skin was assessed. After 30 days, participants showed significant increases in skin elasticity (11.8% increase, p