TITLE:
Analysis of the Effects of Botulinum Toxin Type A to Promote the Survival of Transverse Rectus Abdominis Myocutaneous Flaps in an Animal Model
AUTHORS:
Erika Otilia Haro García, Edna M. Aizpuru, Jorge Eduardo Gutierrez Salgado, Maria Irene Rivera Salgado, Jose Telich Vidal, Olin Carrasco Ortiz
KEYWORDS:
Botulinum Toxin, Tranverse Rectus Abdominis Myocutaneos Flap, Vasodilatation, Survival
JOURNAL NAME:
Journal of Biosciences and Medicines,
Vol.8 No.10,
October
20,
2020
ABSTRACT: The transverse rectus abdominis myocutaneous (TRAM) flap is one of the techniques for breast reconstruction surgery and other defects. Assuring the vascular input is the main factor that it should be ensured for the survival of the fap. Objective: The article presented is an experimental study, with the objective of evaluating the effect of the vasculature on the myocutaneous flaps of the abdominal rectum with botulinum toxin type A (TBoA) thay may improve the survival of the tissue by promoting the blood perfusion in distal parts of the flap and diminish the risk of necrosis. Material and methods: A total of 30 Wistar male rats, dissect pedicled right TRAM flap in all rats, divided into three groups: Group 1 was applied in saline solution 0.9%; Group 2 was applied in pre surgically TBoA (1 week before lifting the flap); Group 3, will apply TBOA Trans surgical. Results: Histological analysis showed: increased vascularity in group 2 TBoA compared with the saline solution with P