TITLE:
Assessment of EEG Changes in Neonatal Sepsis at Al-Zahraa University Hospital’s NIC Unit
AUTHORS:
Sara Tarek Mohamed Mohamed, Zeinab Farag Oshaiba, Marwa El-Hady Abd El Moneim, Asmaa Abd El Wakeel Ibrahim
KEYWORDS:
Background Abnormalities, Electroencephalogram, Neurological Complication, Sepsis Spike, Seizures
JOURNAL NAME:
Open Journal of Pediatrics,
Vol.10 No.3,
September
11,
2020
ABSTRACT: Background: EEG is one of the most sensitive instrumental techniques for identifying
sepsis-related neurological complications and a valuable tool in the ICU when
clinical assessment is difficult. Aim
of the Study: To detect EEG changes in neonates with evidence of sepsis. Patients and
Methods: This was a prospective observational study for detecting EEG changes in cases
of proven neonatal sepsis. This study was conducted at the NICU of Al Zahraa
University Hospital for a period from October 2019 to March 2020. Our studied
neonates were 50. This study included full-term newborns (37 to 42 weeks of
gestational age) with clinical and laboratory evidence of sepsis (early and
late onset). Neonatal birth asphyxia, jaundice, congenital malformations,
suspected inborn error of metabolism and neonates electrolytes disturbances
were excluded from the study. We record EEG changes during 20 min By an
electroencephalogram (EEG) with abioelectric amplifier (Deltamed,
Bourgogne), (Philips) Screen. Results: Among our studied neonates (neonates with evidence sepsis), 44.0% developed
clinical seizures, 81% of the seizures group had abnormal EEG, 35.7% of No
seizures group had abnormal EEG. Among our studied neonates, 56% had abnormal
EEG EEG abnormalities were as follow, 26%/ had low voltage, 30% had spikes, 22%
had sharp waves. Conclusion: About
35% (one third) of neonates who didn’t develop clinical seizures had abnormal
EEG, suggesting a poor correlation between clinical and electroencephalographic
detection of seizures.