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Carithers, D.S., Halos, L., Crawford, J., Stanford, H., Everett, W. R. and Gross, S.J. (2016) Comparison of Preference Demonstrated by Dogs When Offered Two Commercially Available Oral Ectoparasiticide Products Containing Either Afoxolaner (NexGard^®) or Sarolaner (Simparica^TM). The International Journal of Applied Research in Veterinary Medicine, 14, 217-222.

has been cited by the following article:

• TITLE: Preference of Dogs between Two Oral Formulations of Endectoparasiticides: NEXGARD SPECTRA® (Afoxolaner and Milbemycin Oxime) and Simparica TrioTM (Sarolaner, Moxidectin and Pyrantel)

  AUTHORS: Nadège Perier, Douglas S. Carithers, William Russel Everett, Sheila J. Gross, Phrutsamon Wongnak, Karine Chalvet-Monfray, Frédéric Beugnet

  KEYWORDS: Preference, Parasiticide, Palatability, Dog, Compliance

  JOURNAL NAME: Open Journal of Veterinary Medicine, Vol.10 No.9, September 10, 2020

  ABSTRACT: Pet owner compliance is essential for the success of veterinary healthcare strategies. As some parasites are zoonotic, consistent parasite control is an integral part of the One-Health strategy. Highly palatable formulations help ensure compliance, as they offer a positive experience for the dog and the owner. This study was conducted to ascertain if dogs exhibited a preference between two commercially available oral formulations of broad-spectrum endectoparasiticides, NexGard Spectra (afoxolaner and milbemycin oxime) and Simparica Trio (sarolaner, moxidectin and pyrantel). For four consecutive days, 100 healthy dogs were offered both products and consumption was recorded. If one product was more consumed than the other, it was defined as the preferred product. No adverse event was recorded throughout the study. A total of 358 chewable tablets were consumed over four study days; 78.5% of dogs voluntarily consumed NexGard Spectra (281 chews), while 21.5% of dogs voluntarily consumed Simparica Trio (77 chews, p p -16), resulting in a preference ratio of 17.75 to 1 for NexGard Spectra.