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Hemmila, M.R., Rowe, S.A., Boules, T.N., Miskulin, J., McGillicuddy, J.W., Schuerer, D.J., Haft, J.W., Swaniker, F., Arbabi, S., Hirschl, R.B. and Bartlett, R.H. (2004) Extracorporeal Life Support for Severe Acute Respiratory Distress Syndrome in Adults. Annals of Surgery, 240, 595-605.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1356461/
https://doi.org/10.1097/01.sla.0000141159.90676.2d

has been cited by the following article:

• TITLE: Outcomes of Extracorporeal Membrane Oxygenation in Blood Culture Positive Septic Patients

  AUTHORS: Cameron Blazoski, Qiong Yang, Hitoshi Hirose

  KEYWORDS: Extracorporeal Membrane Oxygenation, Shock, Sepsis

  JOURNAL NAME: World Journal of Cardiovascular Surgery, Vol.10 No.8, August 31, 2020

  ABSTRACT: INTRODUCTION: Extracorporeal membrane oxygenation (ECMO) is commonly used for refractory cardiac or respiratory failure. There are reported cases of successful use of ECMO in patients with septic shock; however, there is a lack of evidence to prove its overall efficacy. Thus, we conducted this study to analyze the relationship between sepsis and ECMO in our own patients. METHODS: 305 patients who were placed on ECMO between 2010 and 2020 were identified within an IRB-approved database. Their clinical outcomes were analyzed with a specific focus on patients who were septic before or during ECMO, defined as a positive blood culture. Group S was composed of patients with a positive blood culture before or during ECMO, while Group N was composed of all patients without a positive blood culture before or during ECMO. The primary outcome compared between groups was ECMO survival rate. RESULTS: Among the 305 patients on ECMO, 58 (19%) were in Group S and 247 (81%) were in Group N. ECMO survival rates were 45% in Group S and 62% in Group N (p = 0.017). CONCLUSION: Of our 305 patients, patients who were septic upon ECMO placement or those who developed sepsis during ECMO had worse ECMO survival rates than non-septic patients. Ultimately, patients who are septic or have a high probability of becoming septic may not be indicated for ECMO placement, and cautious administration of ECMO to these patients may be necessary.