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Rosenberg, A.A., Haft, J.W., Bartlett, R., Iwashyna, T.J., Huang, S.K., Lynch, W.R. and Napolitano, L.M. (2013) Prolonged Duration ECMO for ARDS: Futility, Native Lung Recovery, or Transplantation? American Society for Artificial Internal Organs Journal, 59, 642-650.
https://doi.org/10.1097/MAT.0b013e3182a9e341
https://journals.lww.com/asaiojournal/Fulltext/2013/11000/Prolonged_Duration_ECMO_for_ARDS
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has been cited by the following article:

• TITLE: Outcomes of Extracorporeal Membrane Oxygenation in Blood Culture Positive Septic Patients

  AUTHORS: Cameron Blazoski, Qiong Yang, Hitoshi Hirose

  KEYWORDS: Extracorporeal Membrane Oxygenation, Shock, Sepsis

  JOURNAL NAME: World Journal of Cardiovascular Surgery, Vol.10 No.8, August 31, 2020

  ABSTRACT: INTRODUCTION: Extracorporeal membrane oxygenation (ECMO) is commonly used for refractory cardiac or respiratory failure. There are reported cases of successful use of ECMO in patients with septic shock; however, there is a lack of evidence to prove its overall efficacy. Thus, we conducted this study to analyze the relationship between sepsis and ECMO in our own patients. METHODS: 305 patients who were placed on ECMO between 2010 and 2020 were identified within an IRB-approved database. Their clinical outcomes were analyzed with a specific focus on patients who were septic before or during ECMO, defined as a positive blood culture. Group S was composed of patients with a positive blood culture before or during ECMO, while Group N was composed of all patients without a positive blood culture before or during ECMO. The primary outcome compared between groups was ECMO survival rate. RESULTS: Among the 305 patients on ECMO, 58 (19%) were in Group S and 247 (81%) were in Group N. ECMO survival rates were 45% in Group S and 62% in Group N (p = 0.017). CONCLUSION: Of our 305 patients, patients who were septic upon ECMO placement or those who developed sepsis during ECMO had worse ECMO survival rates than non-septic patients. Ultimately, patients who are septic or have a high probability of becoming septic may not be indicated for ECMO placement, and cautious administration of ECMO to these patients may be necessary.