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Anastos, K., Shi, Q., French, L.A., Levine, A., Greenblatt, M.R., Williams, C., et al. (2004) Total Lymphocyte Count, Hemoglobin and Delayed-Type Hypersensitivity as Predictors of Death and AIDS Illness in HIV-1 Infected Women Receiving Highly Active Antiretroviral Therapy. Journal of Acquired Immune Deficiency Syndromes, 35, 383-392.
https://doi.org/10.1097/00126334-200404010-00008

has been cited by the following article:

• TITLE: The Pattern of Haematological Changes in the Baseline Blood Cell Counts and the CD4⁺ T Lymphocyte Levels among Antiretroviral Therapy Naïve Adult HIV Positive Patients in a Nigerian Hospital

  AUTHORS: Taiwo Modupe Balogun, Abiola Omosalewa Alao, Olawunmi Femi Olaosebikan, Adewunmi James Aremu, Oladunni Olajumoke Adegbite

  KEYWORDS: Haematology, Complications, HIV Infection, Nigeria

  JOURNAL NAME: Open Journal of Blood Diseases, Vol.10 No.3, August 17, 2020

  ABSTRACT: Background: Haematological abnormalities are strong independent predictors of morbidity and mortality in HIV infection. Objectives of the Study: This study was carried out to assess the pattern of the changes in the baseline peripheral blood cell counts among adult HIV positive patients. To also determine the CD4+ T cell levels and its correlation with the changes in the baseline cell counts of the patients using HIV negative blood donors as controls. Methods: This was a case controlled prospective study. The subjects were antiretroviral therapy naive adult HIV positive patients and HIV negative blood donor controls. Five milliliters (5 mls) of venous blood was collected from the cubitus of every consecutive consenting subject. Blood sample was analysed for baseline complete blood cell counts and the CD4+ T lymphocyte levels using Sysmex and Cyflow R Counter autoanalysers respectively. Obtained data was analysed with the statistical package for the social scientist (SPSS version 20.0). The Erythrocyte sedimentation rate of subjects was measured by the manual standard Westergreen method. Results: Of 300 subjects, there were 139 (46.3%) males and 161 (53.7%) females in the study. Anaemia was found in 72 (29.2%), leucopenia in 20 (8%) and thrombocytopenia in 6 (2.4%) of the patients. The mean erythrocyte sedimentation rates of the subjects were 81.88 mm/hr and 9.46 mm/hr (p = 0.000) for the patients and the controls respectively. The mean CD4+ T lymphocyte cell counts were 293 cells/μl and 750 cells/μl (p = 0.000) for the patients and controls respectively. Conclusion: Anaemia, leucopenia and thrombocytopenia were more prevalent among the studied HIV positive patients.