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Nayyar, S., Downar, E., Beheshti, M., Liang, T., Massé, S., Magtibay, K., Bhaskaran, A., Saeed, Y., Vigmond, E. and Nanthakumar, K. (2019) Information Theory to Tachycardia Therapy: Electrogram Entropy Predicts Diastolic Microstructure of Reentrant Ventricular Tachycardia. American Journal of Physiological-Heart and Circulatory Physiology, 316, H134-H144.
https://doi.org/10.1152/ajpheart.00581.2018

has been cited by the following article:

• TITLE: Biological Stress as a Principle of Nature: A Review of Literature

  AUTHORS: Celia Martins Cortez, Dilson Silva

  KEYWORDS: Stress Concept, Biological Stress, Thermodynamic Entropy, Information Entropy, State of Stress

  JOURNAL NAME: Open Journal of Biophysics, Vol.10 No.3, July 22, 2020

  ABSTRACT: This review paper attempts to approximate the concept of biological stress to the stress concept in Physics using the phenomenological view of physics to discuss the source of generator forces of biological stress state. Based on the literature, parallels are drawn between the two concepts and a discussion on the steady state in open systems and homeostatic state in biological systems is developed. Using the concepts of thermodynamic entropy and informational entropy, and comparing stress in living systems and nonliving, we attempt to build a basis for a view of stress as a principle of nature linked to the adaptability property of matter, opposing entropy. It is known that the increasing number of microstates possible in a complex system increases the entropy. In that way, entropy is related to the amount of additional information needed to specify the exact physical state of a system, given its macroscopic specification. By controlling the metabolic processes (catabolism-anabolism) to decrease the entropy, stress reduces the number of possible states for which the living system could evolve, avoiding the loss of “life information”, preserving its characteristics and preventing its extinction. The loss of function of a species within an ecosystem or of cells within an organ can be showing that the limits of the stress principle were “transgressed”. That is, the intensity and/or duration of stress exceeded the capacity of living organism to process of information extracted from stressor and reprogram its physiological mechanisms, activating its adaptability process, while its internal balance is preserved.