TITLE:
Using Bacterial Vectors for Probable Vaccines: From Molecular Mechanism to Cancer Therapy
AUTHORS:
Parnia Jabbari
KEYWORDS:
Bacterial Vector, Vaccine Delivery System, Cancer Vaccine, DNA Vaccine, Tumor
JOURNAL NAME:
World Journal of Vaccines,
Vol.10 No.2,
May
30,
2020
ABSTRACT: Anti-cancer therapies over the few decades, faced with many challenges. And bacterial vaccine vectors have shown a potential to be replaced as the cutting-edge technology for such aspects. Bacterial vaccine vectors with a suitable DNA can be a potential option for cancer treatment as a carrier for tumoricidal agents or bacterially directed Enzyme Prodrug treatment. Throughout this study, it is planned to have a review of the use of bacteria as vehicles by different ways for cancer treatment, detailing the systems of function and achievements at preclinical and clinical levels.