TITLE:
Acute Coronary Syndrome in a Young Male Secondary to Hyperhomocysteinemia
AUTHORS:
Kiran Prasad Acharya, Chandra Mani Adhikari, Dipanker Prajapati, Sachin Dhungel, Amrit Bogati, Mohamed Shaneez Najmy, Pratima Poudel, Deewakar Sharma
KEYWORDS:
Hyperhomocysteinemia, Young, Myocardial Infarction, Risk Factors
JOURNAL NAME:
World Journal of Cardiovascular Diseases,
Vol.10 No.7,
July
14,
2020
ABSTRACT: Homocysteine is sulfur containing intermediary amino acid formed by the demethylation of dietary methionine to cysteine. The raised serum homocysteine level is one of the important risk factors associated with coronary artery disease.We present a 23-year-old male with no other risk factors of coronary artery disease presented to us with acute anterior wall myocardial infarction and was treated with primary percutaneous coronary intervention. During the routine work up post percutaneous coronary intervention significant elevation of serum homocysteine level was seen with markedly low serum vitamin B12 level and was treated for it along with standard therapy for acute myocardial infarction.The case illustrates the need to incorporate a plasma homocysteine level during work up of coronary artery disease especially in young patients, more importantly in those without any conventional risk factors.