TITLE:
Tissue Doppler Study before and after PCI in Patients with Chronic Stable Angina and Apparent Normal Ventricular Function for Evaluation of Myocardial Function
AUTHORS:
Hossam Eldin M. Mahmoud, Ahmed Boghdady, Mohamed A. Alsenbesy, Alaa A. Ghalib, Ahmed Okasha, Huda A. Dardeer, Ahlam M. Sabra
KEYWORDS:
Doppler Tissue Imaging, Coronary Artery Disease, Percutaneous Coronary In-tervention
JOURNAL NAME:
World Journal of Cardiovascular Diseases,
Vol.10 No.7,
July
14,
2020
ABSTRACT: Background:This study aimed to
determine the impact of the percutaneous coronary intervention (PCI) on
myocardial function assessed by tissue Doppler echocardiography. Methods: Conventional
two-dimensional echocardiography and Myocardial tissue peak
velocities were recorded at the lateral, ant.septal, post.septal, posterior,
ant. and inferior angles of the mitral annulus as well as at the lateral
tricuspid annulus by pulsed-wave tissue Doppler echocardiography before PCI, as
well as 1 day and 6 weeks after intervention. Results: Fifty consecutive
patients with chronic stable angina and preserved
systolic left ventricular function (mean age, 58.3 ± 6.594 years; 32 men)
undergoing PCI were studied. Conventional echocardiographic revealed no
statistically significant difference between pre- and post-PCI (1 day after PCI
and 6 weeks after PCI) as regarding trans-mitral and trans-tricuspid
flow velocities except as regarding LVEDD, LVESD and LVEF which showed a
significant improvement post-PCI. Compared with pre-interventional values,
systolic peak velocity and early diastolic velocities improved at all sites (P
≤ 0.05 for each). The most pronounced improvement occurred in the septal
area. Similarly, late diastolic velocities improved at all sites (P ≤ 0.05 for each) except
at post Wall A’. Also, there was a significant improvement of E’DT & E’/A’
ratio after PCI (P value is significant 0.05 for each). There were significant reductions in IVRT, IVCT & MPI
after PCI (P value is significant Conclusions: Tissue Doppler parameters of diastolic and systolic function improve
early after successful PCI, and this effect persists to 6 weeks after the
intervention that emphasizes its value in the improvement of regional and
global LV functions and myocardial contractility.