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Chan, C.T., Blankestijn, P.J., Dember, L.M., Gallieni, M., Harris, D.C.H., Lok, C.E., Mehrotra, R., Stevens, P.E., Wang, A.Y., Cheung, M., Wheeler, D.C., Winkelmayer, W. and Pollock, C.A. (2019) Dialysis Initiation, Modality Choice, Access, and Prescription: Conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney International, 96, 37-47.
https://doi.org/10.1016/j.kint.2019.01.017

has been cited by the following article:

• TITLE: Prevalence and Determinants of Gastrointestinal Symptoms in Adults on Maintenance Hemodialysis in Cameroon

  AUTHORS: Francois Folefack Kaze, Mathurin Pierre Kowo, Ethel Ngweh-Awah Anyu Ndikum, Hermine Danielle Menye Ebana Fouda, Victorine Nzana, Emmanuelle Ndjong, Marie Patrice Halle

  KEYWORDS: Gastrointestinal Symptoms, Adults, Hemodialysis, Cameroon

  JOURNAL NAME: Open Journal of Nephrology, Vol.10 No.3, July 8, 2020

  ABSTRACT: Introduction: Gastrointestinal symptoms (GIS) are common in patients on maintenance hemodialysis and constitute an important cause of morbidity. Objectives: To determine the prevalence of GIS and identify their determinants in adults on maintenance hemodialysis in Cameroon. Patients and Methods: This hospital-based cross-sectional study was conducted from January to May 2017 at the Yaounde University Teaching Hospital dialysis center. All conscious consenting adults’ patients who provided a written informed consent and have been on hemodialysis for more than three months with an arterio-venous fistula were recruited. All chronic hemodialysis patients of the center dialyze 4 hours twice a week. All patients with dementia were excluded. We collected demographic, clinical, and paraclinical data and used Rome IV modified GIS rating scale. Parametric and non-parametric tests were used to compare variables. Results: We included 83 (72.3% males) participants with a mean (SD) age of 50 (12) years. Hypertension (31.3%), chronic glomerulonephritis (26.5%) and diabetes mellitus (20.5%) were the leading baseline nephropathy. There were 31 (37.3%) participants with psychiatric disorders including anxiety (45.2%) and depression (54.8%). The biological abnormalities were increased parathormone (20.5%), hypocalcemia (24.1%), hyperphosphatemia (32.5%), increased C-reactive protein (46.4%) and anemia (68.7%). The GIS was reported in 73 (87.9%) participants. Diarrhea (47%), constipation (38.6%), vomiting (38.6%), anorexia (33.7%) and nausea (31.3%) were the main GIS observed. The presence of hypertension was the only association with the GIS (p = 0.02). We did not find any association between GIS and age, gender, diabetes mellitus, psychiatric disorders and duration in dialysis (all p > 0.1). Conclusion: We reported a high prevalence of GIS in this mainly young adult population. This could be related to their under-dialysis status and suggest the increased frequency of dialysis session in this setting.