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Wong, V.W., Rustad, K.C., Akaishi, S., Sorkin, M., Glotzbach, J.P., Januszyk, M., Nelson, E.R., Levi, K., Paterno, J., Vial, I.N., Kuang, A.A., Longaker, M.T. and Gurtner, G.C. (2011) Focal Adhesion Kinase Links Mechanical Force to Skin Fibrosis via Inflammatory Signaling. Nature Medicine, 18, 148-152.
https://www.ncbi.nlm.nih.gov/pubmed/22157678
https://doi.org/10.1038/nm.2574

has been cited by the following article:

• TITLE: Technological Advances in Accelerated Wound Repair and Regeneration

  AUTHORS: Xanya Sofra, Nuris Lampe

  KEYWORDS: Keloids, Acute Wounds, Hypertrophic Scars, Inflammation, Eschar Wounds, Herpes Zoster, Aging, Wound Healing, Diabetic Lesions

  JOURNAL NAME: Health, Vol.12 No.7, July 6, 2020

  ABSTRACT: We reviewed a number of wound repair, keloid and hypertrophic scar research methods that included lasers, microcurrent and ultra-low energy technologies. Laser research reports short-term improvement in wounds, keloid and hypertrophic scars, but without follow up to control for reoccurrence of keloids or diabetic lesions which generally reoccur following laser treatments. The microcurrent and ultra-low energy studies demonstrate significant healing where age is not a factor with no reoccurrence of diabetic wounds and other skin lesions. Our randomized, double-blind longitudinal research on eight wound repair clinical cases with an age range of 28 - 86, followed for one year, evidenced accelerated healing and no reoccurrence. The number of treatments required for substantial healing depended on the chronicity and severity of the lesion, with chronic severe lesions requiring more treatments, rather than age, a conclusion supported by ultra-low microcurrent research. These results on age-independent wound healing directly contradict a large body of literature postulating that healing is much slower with age due to immune insufficiency, age-accumulated oxidative stress, disrupted cell communications and sustained inflammation.