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M. DeBandt, V. Ollivier, O. Meyer, C. Babin-Chevaye, F. Khechai, D. de Prost, J. Hakim and C. Pasquier, “Induction of Interleukin-1 and Subsequent Tissue Factor Expression by Anti-Proteinase 3 Antibodies in Human Umbilical Vein Endothelial Cells,” Arthritis Rheum, Vol. 40, No. 11, 1997, pp. 2030-2038.
doi:10.1002/art.1780401116
has been cited by the following article:
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TITLE:
A Fatal Case of Treatment-Related Adverse Effects in Granulomatosis with Polyangiitis (Wegener’s Granulomatosis)
AUTHORS:
Marina Magrey, Maria Antonelli
KEYWORDS:
Granulomatosis with Polyangiitis, Wegener’s Granulomatosis, Cerebrovascular Accident, Infection, CNS Manifestation
JOURNAL NAME:
Open Journal of Rheumatology and Autoimmune Diseases,
Vol.1 No.2,
November
29,
2011
ABSTRACT: Well-studied therapies have proven to be effective in treating Granulomatosis with polyangiitis (formerly Wegener’s granulomatosis) (GPA). There has been considerable improvement in survival of patients with GPA but treatment related morbidity and mortality remains still high, particularly in patients with renal disease. We describe a case of 64-year old woman with recent onset GPA, who responds well to the initial cyclophosphamide based therapy but latter develops a fatal stroke. Infectious complications should be considered in patients with GPA who are on adequate immunosuppression but develop symptoms that may mimic a relapse. Aggressive diagnostic interventions should be undertaken to discriminate between an infection and a relapse of GPA.