TITLE:
Value of Pulsed Tissue Doppler Imaging in Predicting the Presence of Significant Coronary Artery Insufficiency
AUTHORS:
Hossam Eldin M. Mahmoud, Ahlam M. Sabra, Mohammad Shafiq Awad, Ahmed Hussein
KEYWORDS:
Tissue Doppler Imaging, TDI, CAD, Mitral Annular Velocities, S'-Wave Dispersion, Coronary Artery Disease, Coronary Angiography
JOURNAL NAME:
World Journal of Cardiovascular Diseases,
Vol.10 No.5,
May
13,
2020
ABSTRACT: Background: Coronary artery disease (CAD) is a paramount cause of death. Global and regional left ventricular (LV) systolic function is an important non-invasive marker of CAD. We can use tissue Doppler imaging (TDI) to measure the low velocities generated by myocardium which are: S'-wave, E'-wave, and A'-wave. We aimed to examine the value of the S'-wave dispersion of TDI across mitral valve annular velocities to predict angiographically significant coronary artery obstruction. Patients and Methods: We included 100 patients with symptoms suggesting CAD. All patients had undergone full history taken and clinical examination; ECG, echocardiographic with assessment of LV function, and Doppler derived mitral valve velocities; TDI with measuring of S'-wave and coronary angiography. Lesions with ≥70% or more stenosis in major epicardial artery or ≥50% stenosis in the left main coronary artery were considered significant. Patients were classified into two groups according to the presence or absence of significant coronary stenosis. Results: Clinical and conventional echocardiographic and Tissue Doppler measures were comparable between the two groups; there was statisticallysignificant difference between Group I and Group II (P value ; patients with significant coronary arteries lesions have higher S' wave dispersion as compared with patients with normal or mild significant coronary lesions. Conclusion: S'-wave dispersion may consider a good predictor of angiographically significant coronary artery disease.