TITLE:
Evolution of Graves’s Disease: Impact of Socio-Demographic and Clinical Factors in Senegalese Subject
AUTHORS:
Djiba Boundia, Diedhiou Demba, Sow Djiby, Ndour Michel Assane, Diallo Ibrahima Mané, Barrage Ahmed Limane, Ka-Cissé Mariama, Sarr Anna, Ndour-Mbaye Maimouna
KEYWORDS:
Graves’s Disease, Profile, Gender, Age, Senegal
JOURNAL NAME:
Open Journal of Internal Medicine,
Vol.10 No.2,
May
11,
2020
ABSTRACT: Background: In Graves’s disease, there is a lack of description specific to the gender and age among sub-Saharan African subject. The objective was to evaluate the impact of gender and age on the profile of Graves’ disease in Senegalese subject in order to understand the evolution and improve the therapeutic choices. Methods: This is a retrospective study conducted from January 1, 2010 to December 31, 2017 (07 years) at Abass Ndao University Hospital (Senegal), focused on patients with Graves’ disease followed up under antithyroid drugs treatment for at least 18 months. Results: There were 244 men, 404 subjects between [0 - 25 years], and 101 subjects more than 50 years old. Factors associated with goitre size were male gender (p Conclusion: In our Senegalese study, men and young patients are particularized by a trend of voluminous goitre and low rate of remission. These data remain a basis for predicting the outcome of medical treatment and make timely use of radical treatments such as surgery or irratherapy in the presence of risk factors for recurrence.