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Kostis, J.B., Kim, H.J., Rusnak, J., Casale, T., Kaplan, A., Corren, J., et al. (2005) Incidence and Characteristics of Angioedema Associated with Enalapril. Archives of Internal Medicine, 165, 1637.
https://doi.org/10.1001/archinte.165.14.1637

has been cited by the following article:

• TITLE: Angiotensin-Converting Enzyme Inhibitor Induced Angioedema Occurring after 8 Years of Taking Lisinopril: A Case Report

  AUTHORS: Wade Jodeh, Gregory Stone

  KEYWORDS: Angioedema, Angiotensin Converting Enzyme Inhibitor, Lisinopril, Eight Years

  JOURNAL NAME: Case Reports in Clinical Medicine, Vol.9 No.5, April 22, 2020

  ABSTRACT: Angiotensin-converting enzyme inhibitor induced angioedema (AIIA) can vary from mild to life-threatening. A vast majority of cases of AIIA occur within a month of starting an angiotensin-converting enzyme-inhibitor (ACE-I). We present a 48-year-old male who presented with respiratory failure secondary to AIIA, after being on lisinopril for over 8 years. He had no previous complications secondary to lisinopril and aside from smoking, carried no risk factors for AIIA. Despite conventional treatment for angioedema, he had a prolonged stay in the Medical Intensive Care Unit (MICU). Following discharge, there hasn’t been a recurrence of AIIA since the discontinuation of lisinopril. The case is intended to caution that AIIA remains possible even late into a chronic regimen of ACE-I. This is a risk that shouldn’t be neglected, even with sparse risk factors or longer duration of ACE-I use. Conventional treatment is not currently in line with proposed etiologies of AIIA. We advocate for more clinical trials involving pharmaceutical agents targeting bradykinin accumulation.