TITLE:
Non-Alcoholic Fatty Liver Disease as a Coronary Heart Disease Severity Predictor
AUTHORS:
Hossam Ismael, Mohammed Tag-Adeen, Ahmed Abdel-Rady, Mohamed Shazly, Ahmed Hussein
KEYWORDS:
NAFLD, FibroScan, Gensini Score
JOURNAL NAME:
International Journal of Clinical Medicine,
Vol.11 No.4,
April
17,
2020
ABSTRACT: Background and Aim: Association of non-alcoholic fatty liver disease (NAFLD) and liver related mortality is well-known; however; its cardiovascular risk remains questionable. The aim of this work was to highlight the association between NAFLD and the severity of coronary heart disease. Method: The study was conducted between July and December 2019 at Qena university hospital, Qena, Egypt on patients who were scheduled for coronary angiography. Liver steatosis was diagnosed using FibroScan and the severity of coronary artery occlusion was assessed by Gensini score calculation. Statistical analysis was done to study the correlation between liver steatosis and angiography findings. Result: A total of 100 patients were included, mean age 48 years (±8 SD). Correlation between coronary angiography and the baseline variables revealed statistically significant positive correlation between Gensini score and ALT (p = 0.002), FBS (p Conclusion: NAFLD is an independent cardiovascular risk predictor with statistically significant increase in Gensini score with the higher grades of NAFLD.