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Maini, M.K., Bonic lee, C.K., Lamubia, J.R., Reighat, S., Ogg, G.S., King, A.S., Herber, G.J., Gilson, R., Alisa, A., Williams, R., Vergani, D., Naoumov, N., Ferraric, A. and Bertoletti, A. (2000) The Role of Virus-Specific Cd8t Cells in Liner Damage and Viral Control during Persistent Hepatitis B Virus Infection. The Journal of Experimental Medicine, 191, 1269-1292.
https://doi.org/10.1084/jem.191.8.1269

has been cited by the following article:

• TITLE: Assessment of Lipid Profile and Atherogenic Indexes of Hepatitis B Virus Carriers amongst Volunteer Blood Donors in Nigeria

  AUTHORS: Kingsley Kalawari Odiabara, Edna Ogechi Nwachuku, Ndokiari Boisa, Ebirien-Agana Samuel Bartimaeus

  KEYWORDS: Hepatitis, Atherogenic Indices, Lipoproteins, Cardiovascular Disease, Blood Donors

  JOURNAL NAME: Journal of Biosciences and Medicines, Vol.8 No.4, April 15, 2020

  ABSTRACT: Introduction: Infectious agents such as hepatitis B virus can constitute major public health problems as ii affects the liver resulting into inflammatory conditions. This study was designed to assess plasma lipid profile and atherogenic indexes of hepatitis B virus carriers among voluntary blood donors in North Central, North East and South-South regions of Nigeria. Materials & Methods: A total of 183 blood samples were collected from subjects in North Central consisting of 137 males and 46 females; 176 blood samples from the North East consisting of 129 males and 47 females and 173 blood samples from subjects in South-South region consisting of 123 males and 50 females. The mean ages of the subjects were 34.89 ± 9.19 years, 39.81 ± 9.60 years and 39.92 ± 9.27 years for North Central, North East and South-South regions respectively. The specimens were tested for hepatitis B surface antigen using enzyme-linked immunosorbent assay. All specimens were analyzed for total cholesterol, HDL-C, LDL-C and triglycerides with standard biochemical procedures. The atherogenic indexes were computed using established ratios. The data was analyzed statistically and p-value Results: The mean values of total cholesterol, high density lipoprotein cholesterol, low density lipoprotein cholesterol, and triglycerides did not vary significantly (p > 0.05) between the hepatitis B positive carriers and hepatitis B negative subjects across the geo-political zones studied although in some of the parameters the values were on the high normal range between the male and female subjects. The AIP and CRR-1 and CRR-11 of the blood donors in the zones in both the HBsAg positive and negative subjects were within the reference range. The atherogenic coefficient value of >3.0 was obtained for some HBsAg negative and positive subjects in some of the zones. Conclusion: The findings thus indicate that asymptomatic HBV infection may be associated with low risk of dyslipidaemia in the population.