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Zohoncon, T., Bado, P., Ouermi, D., Traoré, E.M., Ouattara, S., Djigma, F., Traoré, I., Yonli, A.T., Obiri-Yeboah, D., Ouédraogo, C., et al. (2016) Molecular Characterization of High-Risk Human Papillomavirus Genotypes Involved in Invasive Cervical Cancer from Formalin-Fixed, Paraffin-Embedded Tissues in Ouagadougou, Burkina Faso. International Journal of Current Research, 8, 39314-39318.

has been cited by the following article:

• TITLE: Association between Polymorphisms of Glutathione S-Transferase and Progression to Cervical Cancer in Women from Burkina Faso and Mali

  AUTHORS: Teega-Wendé Clarisse Ouedraogo, Florencia Wendkuuni Djigma, Théodora Mahoukèdè Zohoncon, Boureima Idani, Abdoul Karim Ouattara, Pegdwendé Abel Sorgho, Dorcas Obiri-Yeboah, Prosper Bado, Mah Alima Esther Traore, Birama Diarra, Albert Théophane Yonli, Charlemagne Ouedraogo, Jacques Simpore

  KEYWORDS: Glutathione S-Transferase M1-Null, Cervical Cancer, Burkina Faso, Mali

  JOURNAL NAME: Journal of Biosciences and Medicines, Vol.8 No.4, March 31, 2020

  ABSTRACT: Although persistence of high-risk human papillomavirus infection is the main risk factor, Glutathione S-Transferase highly polymorphic enzyme involved in the metabolism of xenobiotics, is a good candidate gene. The objective of this study was to compare the polymorphisms of Glutathione S-Transferase M1-null in women with cancerous lesions and without lesions. This study consisted of 322 uterine cervix samples of women from Mali and Burkina Faso with Cervical Intra-epithelial Neoplasia 2 and 3, adenocarcinoma and squamous cell carcinoma and 100 women with no lesions. Human Papillomavirus genotyping was performed by Real-time multiplex Polymerase Chain Reaction. Glutathione S-Transferase gene polymorphisms were determined using conventional Polymerase Chain Reaction followed by migration on agarose gel. A statistically significant association with high relative risks of 10.77 for the development of High grade Superficial or Squamous Intra-epithelial Lesion (95% CI = 5.59 - 20.72; p