TITLE:
Evaluation of Multiparametric MRI of the Prostate: Impact of Standardized Examination Protocols and the Endorectal Coil
AUTHORS:
Finn Rampoldt, Frank Huebner, Stephan Zangos, Andreas Bucher, Jan-Erik Scholtz, Moritz Kaup, Sebastian Fischer, Thomas J. Vogl, Boris Bodelle
KEYWORDS:
Prostate Imaging, Prostate Cancer, Multiparametricmri
JOURNAL NAME:
Open Journal of Medical Imaging,
Vol.10 No.1,
February
21,
2020
ABSTRACT: Purpose: The aim of the present study was to evaluate the
patient population, different MRI examination protocols and the patient’s
acceptance of the endorectal coil in the diagnosis of prostate cancer regarding
the current discussion in PI-RADS v2.1. Material
and Methods: In our institute, 256 patients were examined with different protocols
and separated into six groups. The value of
the different MRI protocols was identified by analyzing sensitivity, specificity, negative predictive value and positive predictive value. The patient
population was tested for statistically significant differences in their
characteristics to detect a distortion of the results. The patients’ acceptance of endorectal coil was
evaluated by a query. Results: In total 4.7% of the patients would not recommend a MRI examination because of subjective physical strain and 65.6%
of all patients subjectively saw a benefit in the examination in regard to an
optimal diagnostic process. The protocol groups reached a sensitivity from 66.7% - 100%, a specificity from 40% - 75%, a
positive predictive value from 33.3% - 80% and
a negative predictive value from 66.7% - 100%. Conclusion: MRI of the prostate is a safe and comfortable tool with high sensitivity and negative predictive value
and the potential of ruling out a clinically significant
prostate cancer. However, a general
recommendation for the use of biparametric MRI could not be given, considering a higher sensitivity could be performed
when using dynamic contrast-enhanced MRI or spectroscopy.