TITLE:
Bacteriological Profile of Pneumopathies in Chronic Renal Failure at the University Hospital Center of Point-G in Mali
AUTHORS:
Seydou Sy, Magara Samaké, Hamadoun Yattara, Moctar Coulibaly, Ba Oumou Diallo, Aboubacar Sidiki Fofana, Djénéba Diallo, Atabieme Kodio, Modi Sidibé, Nouhoum Coulibaly, Alkaya Touré, Djibril Sy, Moustapha Tangara, Saharé Fongoro
KEYWORDS:
Renal Failure, Dialysis, Pneumopathy, Mali
JOURNAL NAME:
Open Journal of Clinical Diagnostics,
Vol.10 No.1,
February
14,
2020
ABSTRACT: Introduction: Chronic renal failure (CKD) is defined as a
glomerular filtration rate (GFR) of less than 60 ml/min/1.73m2 for
more than 3 months [1]. Infectious complications are a major source of
morbidity in patients with chronic renal failure. In Mali, we have no data on
pneumopathies in this population, hence the interest of this study. The
objective of this work was to determine the frequency of pneumopathies in
patients with chronic renal failure, describe the clinical radio-types,
identify the microorganisms involved, and assess the renal prognosis of
pneumopathies. Materials and Methods: This was an 18-month prospective
and descriptive study from January 1, 2018 to June 30, 2019 conducted in the
nephrology and hemodialysis department of the University Hospital of Point G.
Included were patients hospitalized during our study period with CKD associated
with pneumopathy on a chest X-ray. Not included were all patients hospitalized
outside the study period, all CKD cases without pneumonia, patients with
incomplete records, and non-consenting
patients. Results: We examined 1111 patients, 35 of whom
presented an image on chest X-ray related to pneumopathy, a frequency of 3.15%
of cases. Twenty-one men (60%) and 14 women (40%) with a sex ratio of 1.5. The
mean age was 46.8 ± 13.9 years with extremes of 23 and 76 years. The types of
pneumopathy on the chest X-ray were: alveolar pneumopathy: 23 cases (65.7%),
pleuropneumopathy: 10 cases (28.6%) and cavitary pneumopathy: 2 cases (5.7%).
Cytobacteriological sputum examination was positive in 65.7%; leukocytes (68.6%
of cases). The germs found were: Klebsiella
pneumoniae (25.7% of cases), Escherica coli (11.4%), Pseudomonas aeruginosa (5.7%), Staphylococcus aureus (5.7%), Citrobacter freundi (5.7%), Enterococus sp. (2.9%), Enterobacter cloacae (2.9%), Candida albicans (5.7%). The search for acid-alcohol-resistant bacilli (BAAR) in sputum was positive in 4 cases (11.4%). There
was an association between the results of cytobacteriological examination of sputum and the results of BAAR testing of sputum (p = 0.046).