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Nair, B., Elmore, A.R. and Cosmetic Ingredient Review Expert Panel (2002) Final Report on the Safety Assessment of Human Placental Protein, Hydrolyzed Human Placental Protein, Human Placental Enzymes, Human Placental Lipids, Human Umbilical Extract, Placental Protein, Hydrolyzed Placental Protein, Placental Enzymes, Placental Lipids, and Umbilical Extract. International Journal of Toxicology, 21, 81-91. https://doi.org/10.1080/10915810290096405

has been cited by the following article:

• TITLE: Improvement of Atrophic Acne Scar and Skin Complexity by Combination of Aqueous Human Placenta Extract and Mesenchymal Stem Cell Mesotherapy

  AUTHORS: Ruchee Phonchai, Pimjai Naigowit, Bunchob Ubonsaen, Supansa Nilubol, Supaluk Brameld, Parinya Noisa

  KEYWORDS: Atrophic Scar, Mesenchymal Stem Cells, Human Placenta Extract, Mesotherapy, Skin, Regeneration

  JOURNAL NAME: Journal of Cosmetics, Dermatological Sciences and Applications, Vol.10 No.1, January 22, 2020

  ABSTRACT: Atrophic scars, a permanent complication of severe acne, have negative effect on psychology in adolescent. The treatment of atrophic scar is depended on types of scar and it is difficult to improve by a single treatment. Mesenchymal stem cell is a scientific approval for surgery scar treatment and wound healing. We present a case report of female presented with atrophic acne scar distributed on both cheeks. The case aims to prove that the combination of MSCs and aqueous human placenta extract (RGF®) contained bioactive therapeutic molecules obviously promoted the improvement of skin scar to reach the optimal outcomes. We first found that MSCs-contained human placenta extract solution combination subcision improves the atrophic acne scar and skin complexity by enhancement of skin cell regeneration.