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Katz, L.J., Erb, C., Carceller Guillamet, A., Fea, A.M., Voskanyan, L., Giamporcaro, J.E., et al. (2018) Long-Term Titrated IOP Control with One, Two, or Three Trabecular Micro-Bypass Stents in Open-Angle Glaucoma Subjects on Topical Hypotensive Medication: 42-Month Outcomes. Clinical Ophthalmology, 12, 255-262.
https://doi.org/10.2147/OPTH.S152268

has been cited by the following article:

• TITLE: Micro-Invasive Glaucoma Surgery with the iStent inject: Impact on IOP and Medication Burden in a Real-World Setting

  AUTHORS: Abdulmajeed Alharbi

  KEYWORDS: iStent inject, MIGS, Glaucoma, Intraocular Pressure, Visual Acuity, Medica-tion Need

  JOURNAL NAME: Open Journal of Ophthalmology, Vol.10 No.1, January 10, 2020

  ABSTRACT: Background: The iStent inject is a Micro-Invasive Glaucoma Surgical (MIGS) device that has shown to reduce IOP and to be safe for glaucoma patients with fewer complications than regular surgery. Objective: To investigate, up to 15 - 20 months, the efficacy and safety of implantation of two second-generation trabecular microbypass stents in patients with or without prior glaucoma surgery. Methods: Fifty-seven eyes were implanted with the iStent inject. The population was comprised of eyes with primary open-angle glaucoma (n = 51), pseudoexfoliation glaucoma (n = 5) and ocular hypertension (n = 1). Major outcome parameters included IOP, medication needs and corrected distance visual acuity (CDVA). Follow-up time points were one day, 2 - 4 months, 9 - 14 months and 15 - 20 months. Results: The main reason to perform MIGS was IOP reduction in 68.4%, reduced number of medications due to drug intolerance in 24.6% and reduced medication due to compliance issues in 7.0% of the eyes. IOP decreased by 22.47%, from 19.40 ± 3.83 mmHg preoperatively (preop) to 15.04 ± 1.67 mmHg at 15-20 months postoperatively. IOP reduction was achieved at all follow-up time points (p Conclusions: Insertion of the iStent inject in patients with or without prior glaucoma surgery shows effective and sustained improvements in IOP with no safety concerns.