TITLE:
A New Supplement for the Treatment of Metabolic Syndrome in Postmenopausal Women
AUTHORS:
Annamaria Giacobbe, Alessandra Bitto, Vincenzo Arcoraci, Roberta Granese, Rosario D’Anna
KEYWORDS:
Metabolic Syndrome, Postmenopause, Insulin Resistance, Cinnamon, Corosolic Acid, Glycyrrhizic Acid
JOURNAL NAME:
Food and Nutrition Sciences,
Vol.11 No.1,
January
7,
2020
ABSTRACT: Background: Metabolic Syndrome (MS) is considered a cluster of metabolic
abnormalities whose pathogenesis is principally attributable to insulin resistance.
Lack of estrogens occurs in postmenopausal women and worsening insulin
resistance and lipid profile, predispose to MS. The aim of the study was to
show whether a new supplement containing cinnamon, corosolic acid and
glycyrrhizic acid may counteract MS manifestations. Methods: A total of 60 postmenopausal women were enrolled in a randomized,
controlled trial; the active treatment group was taking the new supplement for
3 months and was on a hypocaloric diet, control group was only on diet. At the
beginning and after 3 months, metabolic variables were evaluated. Results: After 3 months, a
significant difference in the treated group was observed for glucose, HOMA,
total cholesterol and HDL-cholesterol; whereas, in the control group, a
significant difference was shown only for glucose. After 3 months, a significant difference between groups was
highlighted only for HDL-cholesterol. Conclusion: This study has shown the
naturally occurring components of this new supplement may improve insulin
resistance and lipid profile in a small sample of postmenopausal women.