TITLE:
Frequency of Monthly Ejaculation at Sexual Intercourse, DNA Fragmentation Index and Fertilization Rate among Sperm Donors and Fertility-Challenged Men in Sub-Saharan Africa: Paper 1
AUTHORS:
Abayomi B. Ajayi, Bamgboye M. Afolabi, Victor D. Ajayi, Ifeoluwa O. Oyetunji, Adedamilola Atiba, Seun Saanu, Ayodeji T. Adeoye, Joy Ehichioya, Ibukun I. Ayelehin
KEYWORDS:
Monthly Sexual Ejaculation Rate, DNA Fragmentation Index, Male Infertility, Age Group, Body Mass Index, Social Habits, Black Africans
JOURNAL NAME:
Open Journal of Urology,
Vol.9 No.11,
November
27,
2019
ABSTRACT: Introduction: In humans, the ideal ejaculation frequency depends on age, exercise and sexual potential. Natural ejaculation frequency balances the testosterone levels in the body. Materials and Methods: Semi-structured questionnaire was used to collect information from subjects. Semen samples were collected from sperm donors and sub-fertile men who presented for infertility challenges. Processing and analysis of semen samples were done according to World Health Organization guidelines. Sperm DNA fragmentation was evaluated using the Halosperm®kit. Results: A total of 114 subjects, including 19 sperm donors and 95 sub-fertile males were studied. There was a significant difference (t =−5.96, P-value = 0.00001) in the mean [±sd] age of sperm donors (30.8 [8.1]) and that of sub-fertile men (42.3 [76]). There was a significant difference (t=−4.10, P-value = 0.0005) in the mean monthly ejaculation during sexual intercourse (MESI) among sperm donors with DNA fragmentation index −2.20, P-value = 0.02) in MESI among sub-fertile men aged ≥40 years (8.9 [4.6]) than among those aged −0.67, SE = 0.28, t = −2.40, P-value = 0.02, 95% CI: −1.24,−0.10). Conclusion: In men