Article citationsMore>>

Dimmock, J.R., Nyathi, C.B. and Smith, P.J. (1979) Synthesis and Bioactivities of 1-(hydroxyphenyl)-I-nonen-3-ones and Related Ethers and Esters. Journal of Pharmaceutical Science, 68, 1216-1221.
https://doi.org/10.1002/jps.2600681006

has been cited by the following article:

• TITLE: Mannich-Type Reaction of Aldimines with 2-Silyloxydienes Catalyzed by Ammonium Chloride

  AUTHORS: Shoichi Fukumoto, Miho Shigenobu, Kaori Ishimaru

  KEYWORDS: Mannich-Type Reaction, Ammonium Chloride, Imine, 2-Silyloxydiene

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.9 No.4, November 26, 2019

  ABSTRACT: Reaction of imines with 2-silyloxydiene catalyzed by ammonium chloride has been perfectly proceeded under environmentally friendly conditions to give Mannich-type product selectively. The reaction would proceed via Mannich-type mechanism, not cyclization/ring-opening process. Cyclopropanation of the corresponding Mannich-type product gave the precursor of prasugrel skeleton in high yield.