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Edwards, M.L., Ritter, H.W., Stemerick, D.M. and Stewart, K.T. (1983) Mannich Bases of 4-phenyl-3-buten-2-one. A New Class of Antiherpes Agent. Journal of Medicinal Chemistry, 26, 431-436.
https://doi.org/10.1021/jm00357a020

has been cited by the following article:

• TITLE: Mannich-Type Reaction of Aldimines with 2-Silyloxydienes Catalyzed by Ammonium Chloride

  AUTHORS: Shoichi Fukumoto, Miho Shigenobu, Kaori Ishimaru

  KEYWORDS: Mannich-Type Reaction, Ammonium Chloride, Imine, 2-Silyloxydiene

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.9 No.4, November 26, 2019

  ABSTRACT: Reaction of imines with 2-silyloxydiene catalyzed by ammonium chloride has been perfectly proceeded under environmentally friendly conditions to give Mannich-type product selectively. The reaction would proceed via Mannich-type mechanism, not cyclization/ring-opening process. Cyclopropanation of the corresponding Mannich-type product gave the precursor of prasugrel skeleton in high yield.