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Bala, S., Sharma, N., Kajal, A., Kamboj, S. and Saini, V. (2014) Mannich Bases: An Important Pharmacophore in Present Scenario. International Journal of Medicinal Chemistry, 2014, Article ID: 191072.
https://doi.org/10.1155/2014/191072

has been cited by the following article:

• TITLE: Mannich-Type Reaction of Aldimines with 2-Silyloxydienes Catalyzed by Ammonium Chloride

  AUTHORS: Shoichi Fukumoto, Miho Shigenobu, Kaori Ishimaru

  KEYWORDS: Mannich-Type Reaction, Ammonium Chloride, Imine, 2-Silyloxydiene

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.9 No.4, November 26, 2019

  ABSTRACT: Reaction of imines with 2-silyloxydiene catalyzed by ammonium chloride has been perfectly proceeded under environmentally friendly conditions to give Mannich-type product selectively. The reaction would proceed via Mannich-type mechanism, not cyclization/ring-opening process. Cyclopropanation of the corresponding Mannich-type product gave the precursor of prasugrel skeleton in high yield.