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Ratnasiri, A.W.G., Lee, H.C., Lakshminrusimha, S., Parry, S.S., Arief, V.N., DeLacy, I.H., Yang, J.S., DiLibero, R.J., Logan, J. and Basford, K.E. (2019) Trends in Maternal Prepregnancy Body Mass Index (BMI) and Its Association with Birth and Maternal Outcomes in California, 2007-2016: A Retrospective Cohort Study. PLoS ONE, 14, e0222458.
https://doi.org/10.1371/journal.pone.0222458

has been cited by the following article:

• TITLE: Cervicovaginal Inflammatory Cytokines, Obesity and Inter-Pregnancy Interval Negatively Affect Pregnancy Duration in Pregnant Women at High-Risk for Recurrent Spontaneous Preterm Birth

  AUTHORS: Youssef Abdal Zaher, Adel F. Al-Kholy

  KEYWORDS: Preterm Birth, Inter-Pregnancy Interval, Cervicovaginal Fluid, Cytokines, Body Mass Index, Cervical Cerclage

  JOURNAL NAME: Advances in Reproductive Sciences, Vol.7 No.4, November 25, 2019

  ABSTRACT: Objectives: Evaluation of change of cervicovaginal fluid (CVF) cytokines’ levels during pregnancy and its relation to incidence of preterm birth (PTB). Patients & Methods: Pregnant women with history of PTB and cervical length α (TNF-α) and interleukins (IL)-6 and -10 levels. Study outcomes included differences in cytokines’ levels between samples and groups. Results: Sample-I cytokines’ levels were significantly higher in study than control women. Cytokines’ levels in Sample-II were significantly higher in control, while were significantly lower in study women compared to Sample-I. Sixteen study women had PTB and had significantly higher CVF levels of IL-10 and TNF-α estimated in both samples than women had no PTB. Pregnancy duration was negatively correlated with maternal body mass index (BMI) and cytokines’ levels, while was positively correlated with inter-pregnancy interval (IPI). Cytokines’ levels were positively correlated with BMI and negatively correlated with IPI. Short IPI and high TNF-α levels are negative predictors for pregnancy duration. Conclusion: High BMI, short IPI and high CVF inflammatory cytokines’ levels negatively affect pregnancy duration especially in women with history of recurrent PTB. Early prophylactic CC for women at high-risk of SPTB can modulate local immune disturbance, reduce incidence of SPTB and prolong pregnancy duration.