TITLE:
Effect of Exhausting Exercise on Oxidative Stress in Health, Hemodialysis and Professional Sport
AUTHORS:
Knap Bojan, Prezelj Marija, Večerić-Haler Željka
KEYWORDS:
Hemodialysis, Oxidative Stress, Strenuous Exercise, Rowers, Oxidative Stress Athletes, Oxidative Stress Dialysis
JOURNAL NAME:
Natural Science,
Vol.11 No.11,
November
14,
2019
ABSTRACT: The aim of presented
study is to compare parameters of oxidative stress in untrained volunteers,
patients with chronic, non-motor related disease (dialysis patients) and professional
athletes before and after exhaustive exercise. 40 subjects participated in the
study: 14 healthy, untrained subjects, 12 hemodialysis patients and 14
professional rowers. Superoxide dismutase (SOD), catalase (CAT), glutathione
peroxidase (GPx) and non-transferrin bound iron (NTBI) were determined before
and after exercise. Dialysis patients have increased oxidative stress at rest
with highest NTBI, and show adaptation with increased values of GPx and
decreased SOD. Professional athletes have low level of oxidative stress at
basic circumstances with lowest NTBI, SOD, CAT and GPx as compared to untrained
volunteers and dialysis patients. After strenuous exercise elevation of
antioxidative enzymes is observed only in athletes, but not in untrained and
dialysis patients. Due to limited antioxidative capacity, extreme physical
effort is probably not recommended to dialysis patients and untrained people.