TITLE:
A Case Report of Double Malignancy—Recurrent Nasopharyngeal Carcinoma and Adenocarcinoma of the Uterus
AUTHORS:
Ihab E Ali, Farid Razali, Sobani Din, Tang Phing Phing, K. Y. Loh
KEYWORDS:
Multiple, Primary, Malignancies
JOURNAL NAME:
International Journal of Otolaryngology and Head & Neck Surgery,
Vol.8 No.6,
October
25,
2019
ABSTRACT: Multiple primary malignancies (MPMs) is a rare clinical condition where a patient is diagnosed with two or more cancers around the same time. Published literature reported the incidence of multiple primaries is in the range of 2% - 17%. The risk factors for MPMs are smoking, chronic alcoholism, genetic factors and previous treatment of cancer using radiotherapy that may lead to the development of other cancer. This case report describes a rare and unfortunate case of middle-aged Malaysian Chinese lady diagnosed with adenocarcinoma of the uterus and around the same time she had a recurrent nasopharyngeal carcinoma which was first diagnosed and treated 11 years ago. There were no clear risk factors identified in her and she defaulted follow up which eventually led to a fatal complication in which the nasopharyngeal cancer caused massive bleeding in her and she finally succumbed to the complication despite emergency resuscitations.