TITLE:
Management and Clinico-Pathologic Aspects of Non-Melanoma Skin Cancer of the Head and Neck: A Retrospective Institutional Based Study at the Egyptian National Cancer Institute
AUTHORS:
Ihab Samy Fayek, Mohammed Ahmed Rifaat, Dalia Bilal Mohammed
KEYWORDS:
Basal Cell Carcinoma, Squamous Cell Carcinoma, Non-Melanoma Skin Cancer
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.10 No.10,
October
23,
2019
ABSTRACT: Background: Reviewing and analyzing the Clinico-pathologic aspects of non-melanoma skin cancer of
the head and neck (NMSCHN), type of management, prognostic factors, and disease-free survival (DFS) in a period of 5 years at the
National Cancer Institute—Cairo University—Egypt. Materials and Methods: A
retrospective study of two hundred patients with NMSCHN was treated at the National
Cancer Institute—Cairo University—Egypt from January 2008 to December 2012. The
mean follow-up was 6 months (1 - 84
months). Results: 117 males and 83 females with 90% ≥ 50 years old. The
scalp (27.5%), the periorbital region (13%), the cheek (12.5%) and the nose (12.5%)
are the main anatomical sites affected. BCC represented 71.5% with nodular type
(79%) predominance; SCC represented 21% with GII (61.1%) the commonest grade.
Surgery was the main modality of treatment (93%) with local flaps only (63.9%) and primary closure (14.7%) were
the main surgical options following wide local excision. Positive and close
margins were detected in 23.5% of excised specimens. No significant association
was found between disease-free survival (DFS) and pathology, treatment modality,
the occurrence of complications or safety margin status. Conclusion: NMSCHN lesions should be surgically excised in specialized high volume centers
with readily available peripheral margin control and should be operated by
senior experienced surgeons.