TITLE:
Quintuplet Pregnancy: A Rare Case after Clomiphene Citrate Therapy and Review of Literature
AUTHORS:
Bambara Moussa, Ouedraogo Issa, Yaméogo Relwende Barnabe, Tamboura Hassane, Traore Alain Ibrahim, Nikiema Zakari, Nacro Boubacar
KEYWORDS:
Quintuplet Pregnancy, Maternal and Neonatal Consequences
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.9 No.10,
October
18,
2019
ABSTRACT: Multiple pregnancies are
increasing with the progress in Assisted Reproductive Technology. The authors
report a case of quintuplet pregnancy after Clomiphene Citrate stimulation.
This is a 28-year-old woman, G2, P1 with a 4-year-old child alive, who
consulted for maternity desire. She was treated with Clomiphene Citrate at 100
mg daily for five days. The presence of a
quintuplet pregnancy at 8 weeks + 5 days was found by ultrasound on 29/12/2018. During the follow up of the pregnancy,
she presented pre-eclampsia from 24th week (TA 140/100 mmHg, significant
proteinuria, edema of lower limbs). Methyl
Dopa treatment was instituted. Tocolytic treatment with Salbumol was prescribed
facing uterine contractions at 30 weeks. The patient had premature rupture of
membranes at 34 weeks + 4 days, followed by uterine contractions. She had a cesarean section at the same day with the birth of five newborns alive. This is the first
reported case in Burkina Faso.