TITLE:
The Effect of Balanced Hypocaloric Diet on the Anthropometric and Basic Metabolic Indicators in Infertile Women with Gluteofemoral Obesity
AUTHORS:
Natalia V. Artymuk, Natalia A. Sukhova, Olga A. Tachkova, Moamar Al-Jefout
KEYWORDS:
Obesity, Reproductive Age, Infertility, Diet Therapy, Anovulation
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.9 No.10,
October
9,
2019
ABSTRACT: Purpose: To evaluate the effect of balanced hypocaloric diet therapy on the
anthropometric and basic metabolic indicators in obese women with infertility. Methods: The follow up interventional clinical study included 23 infertile women in
reproductive age with grade I gluteofemoral obesity. All patients have prescribed a balanced hypocaloric diet (1200 kcal/day),
underwent exercise and behavioral therapy. Before and after 12-month treatment, an anthropometric study was conducted,
determining the level of metabolic and hormonal indicators. Results: The
total final number of study participants was 20 patients. A decrease in body
weight was achieved in 87% of patients from 4 to 24 kg, on the average, by 10.58 ± 5.70
kg, there was also a decrease in BMI from 32.53 ± 1.40 to 28.55 ± 2.50 kg/m2 (p 0.001). The decrease in
body weight was accompanied by a statistically significant decrease in leptin
levels (p 0.001),
E1 (p = 0.049), E2 (p = 0.032), fasting glucose (p 0.001), HOMA-IR (p =
0.002), cholesterol (p cycles were resumed in all women (p = 0.007) and pregnancy
occurred within a year in 1 patient. Conclusion: The implementation of a
hypocaloric diet for 12 months in infertile women with first-degree obesity helps to normalize metabolic and hormonal
indicators, reduces body weight and restores ovulatory menstrual cycle in all patients.