TITLE:
Non-Neutropenic Sepsis in Cancer Patients: The Luminal Obstruction Syndrome
AUTHORS:
Tamás Kullmann, Dóra Füzi, Tamás Pintér
KEYWORDS:
Sepsis, Biliary Sepsis, Urosepsis, Bronchogenic Sepsis, Solid Cancer
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.10 No.10,
September
29,
2019
ABSTRACT: Background: Neutropenic sepsis is a frequent
complication of cytotoxic chemotherapy delivered for cancer patients. Its
management is well determined by clinical
guidelines. Non-neutropenic sepsis is another potential complication in
cancer patients. Its management is less established in the medical literature. Materials
and Methods: Three cases are presented
to illustrate favourable evolution of
non-neutropenic biliary-, uro- and bronchogenic-sepsis in cancer patients with poor prognosis. Results: All three patients had a survival over six months after the management of the
septic complication. Two of them received
subsequent systemic anticancer treatment. Conclusions: Survival
benefit offered by the management of cancer-related non-neutropenic
sepsis may be comparable to the benefit obtained by systemic anticancer
treatments. Cost-effectiveness of sepsis management may be better than that of
anticancer treatments.