TITLE:
Survival in a Chilean Cohort of Thymic Tumors
AUTHORS:
Mauricio Salinas, Mozart Liessi, Patricio Vallejo, Cristian Ibarra
KEYWORDS:
Thymoma, Thymus Neoplasms, Thymus Gland
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.10 No.7,
July
10,
2019
ABSTRACT: Introduction: Thymus neoplasm is rare
tumors and it has low mortality. There are scarce publications in Latin-American about
this topic. We present a Chilean casuistic. Method: Retrospective cohort of every patient’s thymic
epithelial tumors diagnosed in Instituto Nacional del Tórax, Santiago, Chile,
between January 2007 and June 2015. Information was obtained from pathological
and clinical registries. Death date was achieved from national registry. We report epidemiological data, clinical
manifestations, histology type, Masaoka and WHO classification, therapies and survivor. Results: Sixty-five patients were included, with mean age 58 years and 36.9% men. Myasthenia
gravis was present in 24 (36.9%) of patients. Ninety
four percent of patients had a surgical biopsy. There were 60 thymomas and 5 thymic carcinomas. Most of tumors were stage I and II in Masaoka classification and type B in
WHO classification. There were no deaths at 30 days. Nosocomial pneumonia was
the most common complication. Conclusions: In this thymic tumor cohort there are more women and they are older than previously reported. Myasthenia gravis
prevalence was similar. The survival of patients with thymomas was excellent.