TITLE:
A Meta-Analysis of Danhong Injection in the Treatment of Vascular Dementia
AUTHORS:
Jianhua Chen, Wenzhi Hao, Meichen Zhou
KEYWORDS:
Danhong Injection, Vascular Dementia, Meta-Analysis
JOURNAL NAME:
Journal of Biosciences and Medicines,
Vol.7 No.6,
June
25,
2019
ABSTRACT: Objectives: To evaluate the efficacy of Danhong injection in the treatment of vascular dementia. Methods: CNKI, VIP, CBM, MEDLINE, PubMed, and SCI Expanded databases were searched, and the clinical research literature of Danhong injection in the treatment of vascular dementia was collected. Literature screening and literature quality assessment were performed independently by two investigators based on inclusion criteria and the Cochrane System Evaluator’s Handbook version 5.0.0. Meta-analysis was performed using RevMan 5.0 software. Results: A total of 16 studies were included in a total of 1383 patients. Meta-analysis showed that Danhong injection combined with conventional chemotherapy can reduce the incidence of vascular dementia compared with conventional chemotherapy alone (odds ratio 3.13, 95% CI2.02 to 4.85, P