TITLE:
Endometrial Preparation for Frozen Embryo Transfer by Supplemented Natural Cycle versus Hormone Replacement Cycle in Regularly Cycling Women
AUTHORS:
Suzan Samir Elsharkawy, Tamer Hanafy Mahmoud, Mervat Sheikh-Elarab Elsedeek, Eman Monier Abd Elkader Amer
KEYWORDS:
Intracytoplasmic Sperm Injection (ICSI), Infertility, Frozen Cycles
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.9 No.6,
June
12,
2019
ABSTRACT: BACKGROUND: The first successful pregnancy from a frozen-thawed embryo
transfer (FTET) was reported in 1983 and
after more than three decades, significant changes have been introduced into
clinical practice. OBJECTIVE: To compare endometrial preparation for frozen thawed embryo
transfer (FTET) in supplemented natural cycle (NC) by
hCG (human chorionic gonadotropin) versus HRT (hormonal replacement therapy)
by estrogen and progesterone in regularly cycling women. METHODS:
A prospective trial was conducted on 40 patients that were divided into two
treatment groups. The first group underwent endometrial preparation by
supplemented natural cycle by HCG, and the second group underwent endometrial
preparation by HRT (estrogen and progesterone). RESULTS:
No significant difference was revealed between the two groups regarding ongoing clinical pregnancy
rate. CONCLUSION: This study concluded that there is no significant difference
in clinical pregnancy rate between the two methods of endometrial preparation
for frozen thawed embryo transfer; supplemented natural cycle by hCG or HRT by
estrogen and progesterone, in regularly cycling women.