TITLE:
Anti-Sperm Antibodies: Prevalence of Ig A and Ig G Positive Serology among Infertile Patients in Kisangani, Democratic Republic of Congo
AUTHORS:
Mike-Antoine Maindo Alongo, Juakali Sihalikyolo, Salomon Batina Agasa, Antoine Modia O’yandjo, Bernard Mbutu, Gédéon Katenga Bosunga, Jean-Pascal Manga Okenge
KEYWORDS:
Antisperm Antibody, Immune Infertility, Unexplained Infertility, Democratic Republic of Congo
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.9 No.5,
May
24,
2019
ABSTRACT: Introduction: Infertility in a couple is a stressful situation. Among the
causes is the presence of antisperm antibodies that play a harmful role in
reducing fertility and negatively influencing in vitro fertilization. The aim of this study is to determine their
prevalence among infertile patients in Kisangani. Patients and methods: We
conducted an analytical cross-sectional study in health facilities in the city
of Kisangani. Of the 1379 patients who consulted for conception, 311 were
tested for antisperm antibodies by ELISA. Results: Of the 311 patients, 121
tested positive (38.91%). Women were significantly more likely to be positive
(p-value = 0.013). Ig G was positive in 32.48% of patients and Ig A in 10.93%.
Age was a significant predictor of the number of positive patients (p-value