TITLE:
Gastric Inflammatory Myofibroblastic Tumor in a 10-Year-Old Patient in Macao—Case Report and Literature Review
AUTHORS:
Ieong Chon Man, Kong Soi Chao, Cheng Fai
KEYWORDS:
Computed Tomography, Inflammatory Myofibroblastic Tumor, Stomach
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.10 No.5,
May
8,
2019
ABSTRACT: Inflammatory
myofibroblastic tumor (IMT) is a special type of mesenchymal tumors. The tumors
can occur all over the body. The most common organs involved were lung,
followed by mesentery, omentum, retroperitoneum, and pelvic cavity. But it occurs very rarely in the
stomach. This article mainly reports a 10-year-old patient who complained of
progressive dysphagia for 4 years. Esophagogram suggests esophageal achalasia.
Abdominal CT examination revealed a huge mass with calcification in the cardiac region of stomach with
metastatic lymphadenopathy. PET-CT was also performed that consistent with
malignant gastric tumor with metastatic lymphadenopathy. Gastroscopy also
indicated that there was a huge mass in the cardia that compressed the
esophagus, and biopsy was performed to reveal chronic gastritis. Pathological
analysis was performed after surgical exploration and tissue samples were taken
out and the final pathology was consistent with inflammatory myofibroblastic tumors. The patient was not able
to undergo surgical treatment, so crizotinib chemotherapy was used. After
treatment, the patient's tumors were significantly reduced, and the effect was obvious. The patient is
now in stable condition and continues to follow up. This article hopes to review
the literature of imaging diagnosis of inflammatory myofibroblastic tumors
through this case report, so as to improve the understanding of this disease.