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Gibson, C.M., de Lemos, J.A., Murphy, S.A., Marble, S.J., McCabe, C.H., Cannon, C.P., Antman, E.M. and Braunwald, E. (2001) Combination Therapy with Abciximab Reduces Angiographically Evident Thrombus in Acute Myocardial Infarction: A TIMI 14 Substudy. Circulation, 103, 2550-2554.
https://doi.org/10.1161/01.CIR.103.21.2550
has been cited by the following article:
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TITLE:
Value of Platelet to Lymphocytes Ratio in Predicting Angiographic Reflow after Primary Percutaneous Coronary Intervention in STEMI Patient
AUTHORS:
Ahmed Emara, Neveen I. Samy, Walaa Farid, Mohamed Elgendy
KEYWORDS:
Acute Myocardial Infarction, Primary Percutaneous Coronary Intervention, No Reflow, Platelet Lymphocyte Ratio
JOURNAL NAME:
World Journal of Cardiovascular Diseases,
Vol.9 No.4,
April
25,
2019
ABSTRACT: Background: Acute myocardial infarction is a leading cause of death worldwide nowadays and treatment of choice is primary percutaneous coronary intervention (PCI). No reflow is a complication that increases mortality and morbidity post intervention and one of its predictors is platelet lymphocyte ratio. Aim of Study: To assess relation between admission platelet to lymphocyte ratio (PLR) and angiographic reflow after primary PCI in acute ST elevation myocardial infarction (STEMI). Patients and Methods: This is a prospective study that was conducted from May 2017 to May 2018 at Cardiology Department, Menoufia University Hospital. Sixty patients presented with ST-elevation myocardial infarction who were eligible for primary PCI were enrolled in the study. According to TIMI flow post intervention, patients were arranged into 2 groups: Group 1 (Normal Reflow) included thirty patients with post intervention TIMI flow III and Group 2 (NO Reflow) included thirty patients with post intervention TIMI flow (0, I, II). Comparison between both groups was done regarding platelet lymphocyte ratio (PLR). Result: PLR was significantly higher in patients with coronary no reflow than in patients with normal reflow with a P-value of , timing interval between onset of chest pain to time of intervention and thrombus grading was significantly higher in patients with no reflow than in patients with normal reflow. Conclusion: Pre-intervention PLR is an independent predictor of slow flow/no reflow following PPCI in patient with acute STEMI.